TaiGen Enters Exclusive License Agreement with Joincare for TG-1000 in China
March 29, 2023 at 1:04:23 AM
TaiGen Biotechnology Company, Limited ("TaiGen") today announces that they have signed an exclusive licensing agreement with Joincare Pharmaceutical Group Industry Co., Ltd., a top 10 China pharmaceutical company, to develop and commercialize TG-1000 in China. TG-1000 is a novel pan-influenza antiviral, which interrupts viral replication and transmission via a cap-snatching mechanism to demonstrate broad-spectrum activity against influenza-A, influenza-B, avian flu H7N9, and Tamiflu-resistant viruses.
Upon the agreement takes effect, Joincare will be responsible for the subsequent development, registration, and commercialization of TG-1000 in the territory by undertaking all costs of clinical trials. The territory includes China, Hong Kong and Macao. Under the terms of the agreement, Joincare will make an upfront payment of RMB 20 million and milestone payments, followed by up to 11% of royalties.
TG-1000 is a novel pan-influenza antiviral by interrupting viral replication and transmission via a cap-snatching mechanism, which reveals its efficacy against influenza-A, influenza-B, avian flu H7N9, and Tamiflu-resistant viruses. TG-1000 phase II clinical study has been completed, and the data indicate that TG-1000 effectively alleviate flu symptoms and clear flu viruses.
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